Forge Track 2025

Sponsored by Lonza

Developing a Feedback Control Loop for Miniaturized Cell Culture Systems

For any questions, please contact bioincubate@studentbiolab.ch

CHF 30 000 First Prize | CHF 10 000 Second Prize

Ready to make an impact? Dive into a real-world challenge: developing a precise pH measurement and robust feedback control loop for miniaturized cell culture systems and compete for the grand prize!

This is a multidisciplinary project combining cell biology, bioprocessing, bioengineering, control systems, and software development, so people from all areas of science and engineering are welcome to join!

Who can apply: Teams of 2-6, with at least one active student (Bachelor, Master, PhD). Meaningful time commitment alongside studies/PhD expected.

Want to see the presentations of all the accepted teams and which 2 will be selected to join the Forge program? Then join us at the Forge Selection Event on Thursday, April 3rd!

Timeline:

Ideate Phase: Teams draft their proposal and have the opportunity to meet relevant experts to receive feedback on their ideas. The submission deadline for proposals is Sunday, March 16th at 23:59. Proposals will be screened and the top teams will be invited to pitch in front of a judging panel at the Forge Selection Event. The top two teams will be selected and admitted into the Build Phase.


Build Phase: The two admitted teams will have approximately 5 months to further develop their conceptual solution and basic proof-of-concept according to their proposal. Each team will receive CHF 10,000 project budget, access to a BSL1 laboratory & core facility services in Zürich, and mentorship from experts in Lonza, ETH and UZH.


Final Pitch: The Build Phase will culminate in a Final Pitch in September 2025, when the teams will compete for the 1st Place Grand Prize of CHF 30,000 and 2nd Place Prize of CHF 10,000

FAQ

Q: How often should the pH be measured?

  • Every second to minutes

Q: How fast should the pH be adjusted?

  • A few minutes

Q: Specific condition for the cells?

  • Low light exposure

  • Aseptic environment

  • No phenol red addition

  • Allow for oxygen exchange

Q: Can shaking be stopped for measuring pH?

  • No

Q: Is the pH target the same for all well?

  • Yes, but can change from experiment to experiment

Q: What are the 96 deep well plate dimensions?

Q: What material are the 96 well plates made of?

  • Polypropylene

Q: What kind of shakers are used at Lonza?

  • Different shakers are used. Kuhner ISF1-ZC Peltier should give the dimensions of a typical incubator used. Link to its brochure here Flyer-ISF1-Z-en.pdf

Q: How long does a typical experiment last?

  • 12-15 days

What is Forge?

Students hack to solve a challenge presented by industry to win cash

Read about last year’s challenge, presented by Lonza.